Research
Seminars
Fall 2008
Prof. Donhee Ham
John L. Loeb Associate
Professor of the Natural Sciences
Harvard University
Date: October 17th, 14:30, Interschool Lab (7th
Floor CESPR/Schapiro)
Topic: CMOS RF Biosensor Utilizing
Nuclear Spin Resonance - A Circuit Designer's Approach to Early Disease
Detection
Abstract
I will present our recent work that showcases how
silicon RF chips can be used not only for wireless RF applications, but
also for biosensing aimed at early disease detection. The main function
of our RF chip is to manipulate and monitor RF dynamics of protons in
water via nuclear magnetic resonance (NMR). Target biological objects
such as cancer marker proteins and viruses alter the proton dynamics,
which is the basis for our biosensing. The RF chip has a receiver noise
figure of only 0.6 dB. This high sensitivity made possible our
construction of an entire NMR system around the RF chip in a 2kg
portable platform, which is 60 times
lighter, yet 60 times more sensitive than a state-of-the-art commercial
benchtop NMR system. Sensing one avidin protein molecule in 40 trillion
water molecules, our system is a circuit designer's approach to pursue
early disease detection and improved human healthcare.
Speaker Biography
Donhee Ham is John L. Loeb Associate Professor of the
Natural Sciences and Associate Professor of Electrical Engineering at
Harvard University. He earned his degrees in physics and electrical
engineering, studying at Seoul
National University and California Institute of Technology. His current
research focus is on (1) RF/microwave, analog, and mixed signal ICs,
(2) GHz/THz 1-dimensional electronic and plasmonic transport, (3)
soliton electronics, and (4) applications of CMOS ICs in biotechnology.
Research web: http://www.seas.harvard.edu/~donhee
Donhee Ham: http://www.seas.harvard.edu/~donhee/donheeham.htm
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Date: October 31st, 14:30, 414 CEPSR(Schapiro)
Topic:
Silicon-on-sapphire: mixed-signal circuits and micro-systems design and
opportunities
Abstract
I present a flavor of Silicon-On-Insulator (SOI)
technologies called
Silicon-On-Sapphire (SOS), describing the fabrication process, the
advantages and the basic devices available for circuit and micro-system
design.
The physical differences in the fabrication of the SOS
devices and
the insulating substrate make this process quite different from a
standard bulk process. The insulating substrate, the floating body and
the different thermal properties of the sapphire give rise to
characteristics that have to be fully mastered to allow for the design
of high-performance circuits.
By taking advantage of the features and novelty of this
integrated
circuits process, I will introduce our success stories and a repertoire
of state-of-the-art circuits and systems, such as: analog to digital
conversion systems, ADC architectures, photodetectors, optoelectronic
system, image sensors, biosensor interfaces, patch-clamp amplifiers,
isolation amplifiers, temperature sensors, band-gap references, and
three-dimensional circuits.
Speaker Biography
Eugenio Culurciello (S'97-M'99) received the Ph.D.
degree in Electrical
and Computer Engineering in 2004 from Johns Hopkins University,
Baltimore, MD. In July 2004 he joined the department of Electrical
Engineering at Yale University, where he is currently an assistant
professor. He founded the E-Lab laboratory at Yale University in the
Summer 2004. His research interest is in analog and mixed-mode
integrated circuits for biomedical applications, sensors and networks,
biological sensors, Silicon on Insulator design and bio-inspired
systems.
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Date: November 21st, 14:00, Interschool Lab (7th
Floor CESPR/Schapiro)
Topic: Recent Advances in
Designing Clockless Digital Circuits
Abstract
There has been a resurgence of interest in asynchronous
(i.e. clockless) digital design in recent years, as designers confront
formidable challenges of high-speed clock distribution, chip complexity
power, design time, mixed-timing domains and reusability. Asynchronous
circuits are inherently concurrent, distributed and object-oriented,
and thus promise much greater adaptability in assembling
future-generation digital systems.
This talk is in two parts. In the first part, I will give an
overview of asynchronous design, including motivation, technical
background and highlights of recent successes in industry (Philips,
Fulcrum Microsystems,
Intel, IBM) and academia. I will also briefly survey some active
research areas:
CAD tools for asynchronous circuits and systems, mixed-timing
interfaces, high-speed asynchronous pipelines, and performance
analysis.
In the second part, I will present one of our new design styles for
high-speed asynchronous pipelines, called MOUSETRAP. These
pipelines use simple transparent latches in the datapath, and small
latch controllers consisting of only a single gate per pipeline
stage. This simple stage structure is combined with an efficient
transition-signaling protocol between stages. Extensions to
handling
non-linear structures (fork, join) are introduced to handle more
complex
system architectures. The new pipelines gracefully and robustly adapt
to variable-speed environments, such as due to dynamic voltage scaling.
Post-layout simulations indicate throughputs of 2.1-2.4 GigaHertz in a
conservative 0.18 micron CMOS TSMC process. This
performance is competitive even with that of "wave pipelines",
without the
accompanying problems of complex timing and much design effort.
Speaker Biography
STEVEN M. NOWICK is a Professor of Computer Science and
Electrical Engineering at Columbia University, and Chair of the
Computer Engineering program. He received a Ph.D. in Computer Science
from Stanford University in 1993, and a B.A. from Yale
University. Dr. Nowick's main research focus is on design
methodologies and CAD tools for the analysis, synthesis and
optimization of asynchronous and mixed-timing digital systems.
Dr. Nowick received an NSF Faculty Early Career (CAREER) Award (1995),
an Alfred P. Sloan Research Fellowship (1995) and an NSF Research
Initiation Award (RIA) (1993). He received Best Paper Awards at
the 1991 International Conference on Computer Design and at the 2000
IEEE Async Symposium. He was the recipient of 2
medium-scale NSF ITR awards in 2000 for asynchronous research, and in
2005 was brought onto the DARPA "CLASS" project, headed by Boeing, to
create a new commercially-viable CAD tool flow for designing
asynchronous systems.
Dr. Nowick was also a co-founder of the IEEE Async Symposia series, and
was Program Committee Co-Chair of Async-94 and Async-99 and General
Co-Chair of Async-05, and was Program Chair of the ACM IWLS-02
Workshop. He is an associate editor of IEEE Transactions on
Computer-Aided Design, and formerly associate editor of IEEE
Transactions on VLSI Systems. He is an IEEE fellow.
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Date: November 24th, 11:00, EE Conference Room -
13th Floor Mudd
Topic: Power and Area
Efficient High Speed Analog Adaptive
Equalizers
Abstract
We present a low power analog adaptive equalization
technique suitable for combating inter-symbol-interference at very high
data rates. The proposed technique, which we term the
lumped parameter equalizer, addresses several of the problems
associated with conventional microwave equalizers based on the
tapped delay line structure. The theory is given, and simulation
results comparing it with the performance of ideal tapped delay line
filters are shown. Circuit implementations are discussed,
along with the effect of nonidealities on equalizer performance.
Speaker Biography
Shanthi Pavan received the
B.Tech degree in electronics and communication
engineering from the Indian Institute of Technology—Madras, Chennai,
India, in 1995 and the
M.S and Sc.D degrees from Columbia University,
New York, in 1997 and 1999, respectively.
He has worked at Texas Instruments and Bigbear Networks,
where he researched on high-speed
analog filters and data converters. Since July 2002, he has been with
the Electrical Engineering
Department, Indian Institute of Technology—Madras, where he is an
Assistant
Professor. His research interests are in the areas of high-speed analog
circuit
design and signal processing.
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Date: December 5th, 14:30, Interschool Lab (7th
Floor CESPR/Schapiro)
Topic: Fault Tolerance in
Asynchronous Logic
Abstract
Manufacturing defects or errors due to transient
phenomenon can impact the
correct operation of asynchronous circuits. I will present an overview
of
the impact of these errors on the operation of asynchronous circuits,
and
in particular on quasi delay-insensitive asynchronous circuits. I will
present
a range of techniques for managing different types of failure
mechanisms in
asynchronous circuits.
Speaker Biography
Rajit Manohar is an Associate Professor of Electrical and Computer
Engineering at Cornell, where his group conducts research on
asynchronous design. He received his B.S. (1994), M.S. (1995), and
Ph.D. (1998) from Caltech, and has been on the Cornell faculty since
1998. He is the recipient of an NSF CAREER award, three best paper
awards, five teaching awards, and was named to MIT technology review's
top 35 young innovators under 35. He co-founded Achronix Semiconductor,
a fabless semiconductor company developing high-performance FPGAs.
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